Perdita di grasso e composizione corporea

SLU-PP-332

$475.00

Per vial

$47.50

10 vials per pack

Suggested retail

$142.50

3× markup · per vial

Spedizione gratuita per ordini superiori a 2.000 $

Milligrammi per fiala

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Garanzia di consegna Rispedizione gratuita in caso di mancata consegna
Purezza ≥99% Produzione diretta dal produttore
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Prezzi in base al volume

Prezzo per confezione (10 fiale). Lo sconto si applica solo a questo prodotto: non è possibile combinare diversi articoli.

5 mg

Quantità	Overseas 10-15 days	US 2-3 days	Risparmi
1 confezione	$475	—	—
2 confezioni	$404	—	15% di sconto
3 confezioni	$343	—	28% di sconto
5 confezioni	$309	—	35% di sconto
10 confezioni	$278	—	41% di sconto
25 confezioni	$250	—	47% di sconto

SLU-PP-332 — Pan-ERR Agonist Exercise-Mimetic Research Compound

SLU-PP-332 is a synthetic pan-agonist of the three estrogen-related receptors (ERRα, ERRβ, ERRγ) – orphan nuclear receptors that sit at the center of the transcriptional program exercise activates in skeletal muscle. It was developed at Saint Louis University (the “SLU” in the name) and described in a 2023 publication as a tool compound for probing ERR signaling in vivo. SLU-PP-332 is the reference small-molecule ERR pan-agonist in the current research toolkit – it is not a peptide, and its research utility comes from its ability to transcriptionally upregulate mitochondrial biogenesis and oxidative metabolism without physical training.

Why the Pan-ERR Mechanism Matters

The ERR family (α, β, γ) regulates the transcriptional program that drives mitochondrial biogenesis, oxidative-phosphorylation gene expression, and fatty-acid oxidation capacity. This is the same program exercise training activates. SLU-PP-332’s pan-ERR agonism turns on this program at the transcriptional level, which is why it shows up in published work as an “exercise-mimetic” research compound. It sits at a different point in the mitochondrial-axis toolkit than SS-31 (structural protection) or MOTS-c (AMPK signaling) – it is transcriptional and works upstream of mitochondrial content changes.

Percorso	In parole povere, ecco cosa fa
ERRα / ERRβ / ERRγ	Pan-agonized – full orphan nuclear receptor family transcriptional activation
Mitochondrial biogenesis	Upregulated – PGC-1α axis drives new mitochondrial content
Oxidative phosphorylation	Gene expression increased – greater oxidative capacity
Fatty-acid oxidation	Upregulated – shift toward fat utilization
Exercise-mimetic endpoints	Increased running-endurance time in published rodent studies (no training)

SLU-PP-332 vs Other Mitochondrial-Axis Compounds

The mitochondrial-axis research toolkit has a small group of compounds. They act at different points in the pathway.

Composto	Meccanismo mitocondriale
SLU-PP-332	Pan-ERR agonist – transcriptionally drives mitochondrial biogenesis
MOTS-c	Peptide codificato dal mitocondrio – Attivazione dell'AMPK e segnalazione metabolica
SS-31 (elamipretide)	Cardiolipin binder – structurally stabilizes existing respiratory chain

Applicazioni di ricerca

SLU-PP-332 is used in studies examining:

Pan-ERR agonism and transcriptional mitochondrial biogenesis endpoints
Exercise-mimetic and running-endurance research (without training)
Fatty-acid oxidation and substrate utilization models
Obesity and diet-induced metabolic syndrome research
Comparative mitochondrial-axis research (SLU-PP-332 vs MOTS-c vs SS-31)
ERR pharmacology and orphan nuclear receptor biology

Specifiche tecniche


Formato	Polvere liofilizzata
Purezza	≥99%
Molecular class	Small molecule (not a peptide)
Alias	SLU-PP-332, SLU PP 332, pan-ERR agonist
Archiviazione	2-8 °C se non aperto; stabile per oltre 12 mesi
Utilizzo	Solo a scopo di ricerca – non destinato all'uso umano

Ricostituzione

SLU-PP-332 arrives as a freeze-dried powder. Reconstitute with bacteriostatic water:

Totale in mg nella fiala ÷ ml di acqua aggiunta = mg per ml

Una volta ricostituito, conservare a una temperatura compresa tra 2 e 8 °C e utilizzare entro 28-30 giorni.

Note sul protocollo

The following values are reference points extracted from published SLU-PP-332 research – not instructions. The published in vivo rodent work used daily subcutaneous administration over multi-week windows.

Dose range reported in the rodent literature: ~50mg/kg per administration in the original mouse studies
Frequenza di somministrazione negli studi pubblicati: somministrazione sottocutanea giornaliera
Study durations reported: 4-12 weeks for metabolic and endurance endpoint studies

Common Questions About SLU-PP-332 Research

What is SLU-PP-332 used for in research?

It is studied as the reference pan-ERR agonist research compound. Published work covers transcriptional mitochondrial biogenesis, exercise-mimetic endurance endpoints in untrained animals, fatty-acid oxidation, obesity and metabolic syndrome models, and ERR pharmacology.

Is SLU-PP-332 a peptide?

No. SLU-PP-332 is a small-molecule ligand, not a peptide. It binds directly to the ligand-binding domains of the three ERR nuclear receptors. It appears in the research-compound toolkit alongside peptides because its mitochondrial / exercise-mimetic research axis overlaps heavily with MOTS-c and other peptide-adjacent metabolic compounds.

How does SLU-PP-332 compare to MOTS-c?

Both are studied for mitochondrial endpoints but work at different points in the pathway. SLU-PP-332 acts transcriptionally through pan-ERR agonism – it turns on the gene expression program that builds new mitochondria. MOTS-c acts post-transcriptionally through AMPK activation – it modulates how existing mitochondria operate. Both are “exercise-mimetic” but through distinct mechanisms.

Is SLU-PP-332 FDA approved?

No. SLU-PP-332 is a research tool compound published in 2023 for probing ERR biology in vivo. It is not in clinical trials and has no approved-drug status. Every vial WWP ships is labeled and sold strictly for laboratory and research use only.

How is SLU-PP-332 stored?

Unopened vials are stored at 2-8°C and stay stable for 12+ months. Once reconstituted, store at 2-8°C and use within 28-30 days.

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