BPC-157

Volume Pricing

Price per pack (10 vials). Discount applies to this compound only – no mix and match.

BPC-157 — Gastric Pentadecapeptide / Pleiotropic Cytoprotective & Regenerative Peptide

BPC-157 (Body Protection Compound-157) is a synthetic 15-amino acid pentadecapeptide derived from a protective protein naturally present in human gastric juice. First isolated during research into gastric cytoprotection in the early 1990s, BPC-157 was found to retain the protective properties of its parent compound while exhibiting remarkably broad systemic effects in preclinical models. Its documented activity spans musculoskeletal repair, gastrointestinal protection, vascular remodeling, and central nervous system signaling — making it one of the most mechanistically diverse peptides currently studied in regenerative biology research.

Why BPC-157’s Pleiotropic Profile Matters

Unlike peptides that operate through a single receptor system, BPC-157 engages a network of overlapping molecular pathways simultaneously. This makes it less suited to studies isolating a single mechanism and uniquely valuable for research into how multiple regenerative systems interact and compound within the same model.

A key structural advantage of BPC-157 is its inherent resistance to acidic hydrolysis — a property derived from its gastric origin. This stability has made it a subject of oral administration research in addition to injectable protocols, which is unusual among peptides of this class.

Research Applications

BPC-157 is used in studies examining:

• Tendon, ligament, and muscle repair following acute and chronic injury models
• Gastrointestinal mucosal protection and recovery in IBD and ulceration models
• Angiogenesis and collateral vessel formation following vascular occlusion
• Bone and cartilage healing in fracture and pseudoarthrosis models
• Neuroprotection and functional recovery following spinal cord compression and stroke models
• Gut-brain axis signaling and dopaminergic/serotonergic system modulation
• Comparative oral vs. injectable bioavailability and route-of-administration research
• Combination protocols alongside cytoskeletal agents such as TB-500 (Thymosin Beta-4)

Specifications

Reconstitution

BPC-157 arrives as lyophilized powder and must be reconstituted with bacteriostatic water prior to use. Use the formula:

Total mg ÷ Volume added (mL) = Concentration (mg/mL)

Example: 5mg vial + 2mL BAC water = 2.5mg/mL solution

Reconstituted peptide should be stored at 2–8°C and used within 28–30 days.

Protocol Notes

BPC-157 is notable for its activity across a wide dose range, with preclinical studies reporting significant effects at both nanogram and microgram per kilogram dosing. Its relatively short half-life following parenteral administration (under 30 minutes) is a key variable in protocol design, often addressed through twice-daily dosing schedules or localized administration proximal to the target tissue.

Typical research dosing framework:

• Dose range: 200–500mcg per administration
• Frequency: Once or twice daily depending on endpoint and administration route
• Routes studied: Subcutaneous, intramuscular, intraperitoneal, oral
• Study duration: 2–8 weeks depending on tissue type and injury model

Commonly observed effects in research models:

• GI-related: Generally well tolerated; mild transient nausea reported in limited human data at higher doses
• Local: Injection site irritation; localized administration near target tissue is common in musculoskeletal models
• Other: No minimum toxic dose or lethal dose identified in preclinical safety studies; no genotoxic, teratogenic, or anaphylactic effects reported in animal models to date

Research Stacks

BPC-157 is commonly paired in research settings with:

• TB-500 — BPC-157 promotes angiogenesis and upregulates growth factor expression locally, while TB-500 (Thymosin Beta-4) modulates actin polymerization and systemic anti-inflammatory signaling; the two are studied in combination for their complementary roles in soft tissue repair models.
• GHK-Cu — GHK-Cu stimulates extracellular matrix remodeling and collagen synthesis; research pairs it with BPC-157 to examine additive effects on wound-healing markers and fibroblast activity across tissue types.
• KPV — KPV is a tripeptide with documented anti-inflammatory activity at mucosal surfaces; BPC-157 is co-studied with KPV in gastrointestinal research models where both compounds may act on overlapping inflammatory mediators.

Purity Guarantee

Every batch is ≥99% purity. If you independently test your compound and the results don’t match — send us the COA and we’ll issue store credit, no questions asked.